DISEASE MISCLASSIFICATION IN ELECTRONIC HEALTHCARE DATABASE STUDIES: DERIVING VALIDITY INDICES-A CONTRIBUTION FROM THE ADVANCE PROJECT.

Disease misclassification in electronic healthcare database studies: Deriving validity indices-A contribution from the ADVANCE project.

There is a strong and continuously growing interest in using large electronic healthcare databases to study health outcomes and the effects of pharmaceutical products.However, concerns regarding disease misclassification (i.e.classification errors of the disease status) and its impact on the study results are legitimate.Validation is therefore incr

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Effect of Saccharomyces, Non-Saccharomyces Yeasts and Malolactic Fermentation Strategies on Fermentation Kinetics and Flavor of Shiraz Wines

The use of non-Saccharomyces yeasts to improve complexity and diversify wine style is increasing; however, the interactions between non-Saccharomyces yeasts and lactic acid bacteria (LAB) have not received much attention.This study investigated the interactions of seven non-Saccharomyces yeast strains of the genera Candida, Hanseniaspora, Lachancea

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The formation of a hatching line in the serosal cuticle confers multifaceted adaptive functions on the eggshell of a cicada

Abstract Insect eggshells must meet various demands of developing embryos.These demands sometimes conflict with each other; therefore, there are tradeoffs between eggshell properties, such as robustness and permeability.To meet these conflicting demands, particular eggshell structures have evolved in diverse insect species.Here, we report a rare eg

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Fertility in Namibia. Changes in fertility levels in North-Central Namibia 1960-2001, including an assessment of the impact of HIV

The aim of this study was to estimate the development of fertility in North-Central Namibia, former Ovamboland, from 1960 to 2001.Special attention was given to the onset of fertility decline and to the impact of the HIV epidemic on fertility.An additional aim was to introduce parish registers as a source of data for fertility research in Africa.Da

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